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Mouse metabolism, mouse fat biology, and mouse dosing all differ from the human versions, and metabolic findings in rodents have a long history of not carrying over cleanly to people

Research shows 30% reduction in fat mass, decreased adipocyte size, and normalized plasma cholesterol levels equal to non-obese animals

Now, to understand why this might matter, we need to zoom in on an underappreciated problem in human metabolism

AOD-9604 produces no IGF-1 elevation, potentially making it more appropriate for individuals with cancer history or elevated baseline cancer risk

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